Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.54 |
| ▸ | F2 | P00734 | 5/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | F10 | P00742 | 18/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401264 | 0.93 | PRSS1 (0.53) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7405631 | 0.92 | PRSS1 (0.53) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7405195 | 0.91 | PRSS1 (0.51) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7402318 | 0.91 | F10 (0.53) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7407914 | 0.91 | PRSS1 (0.52) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7408163 | 0.89 | F10 (0.56) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7409644 | 0.86 | F10 (0.59) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7398824 | 0.85 | F10 (0.61) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7405473 | 0.84 | F10 (0.57) | PRSS1F2PRSS2PRSS3F10 | |
| SCHEMBL7406464 | 0.84 | F10 (0.57) | PRSS1F2PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030880-A2 | N-SUBSTITUTED AMINO ACID DERIVATIVES (FACTOR XA INHIBITORS) | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | claimed |
| WO-2002030880-A2 | N-SUBSTITUTED AMINO ACID DERIVATIVES (FACTOR XA INHIBITORS) | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |