SCHEMBL740569

SCHEMBL740569

CN1CCc2nc(C(=O)NC3CCCCC3(N)C(=O)c3cc4cc(Cl)ccc4[nH]3)sc2C1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.72
F2 P00734 4/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL742100 0.99 F10 (0.71) F10F2
SCHEMBL743139 0.99 F10 (0.72) F10F2
Hydrochloric Acid SCHEMBL740567 0.99 F10 (0.71) F10F2
Hydrochloric Acid SCHEMBL1854995 0.99 F10 (0.71) F10F2
SCHEMBL741801 0.98 F10 (0.71) F10F2
Hydrochloric Acid SCHEMBL742420 0.97 F10 (0.70) F10F2
Hydrochloric Acid SCHEMBL744239 0.94 F10 (0.71) F10F2
Hydrochloric Acid SCHEMBL741662 0.94 F10 (0.62) F10F2
Hydrochloric Acid SCHEMBL742089 0.93 F10 (0.61) F10F2
SCHEMBL742396 0.91 F10 (0.60) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431370-A1 Monoacylated 1,2-diaminocycloalkanes DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2012-03-21 EP disclosed
US-7935824-B2 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2011-05-03 US disclosed