Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.64 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6101773 | 0.89 | HTR2C (0.52) | HTR2CHTR6GRIA1EPHX2HRH4 | |
| SCHEMBL3679652 | 0.88 | HTR2C (0.64) | HTR2CHTR6KCNH2GRIA1EPHX2 | |
| SCHEMBL3683092 | 0.82 | HTR2C (0.64) | HTR2CHTR6HRH4 | |
| Hydrochloric Acid SCHEMBL31587078 | 0.81 | HTR2C (0.62) | HTR2CHTR6HRH4 | |
| SCHEMBL3686249 | 0.79 | HTR2C (0.59) | HTR2CHTR6 | |
| Trifluoroacetic Acid SCHEMBL6102191 | 0.79 | HTR2C (0.52) | HTR2CHTR6GRIA1EPHX2HRH4 | |
| SCHEMBL2076366 | 0.78 | HTR2C (1.00) | HTR2CHTR6HRH4 | |
| SCHEMBL30040877 | 0.78 | HTR2C (1.00) | HTR2CHTR6HRH4 | |
| Hydrochloric Acid SCHEMBL1532881 | 0.77 | HTR2C (0.97) | HTR2CHTR6HRH4 | |
| SCHEMBL1729053 | 0.77 | GRM4 (0.40) | HTR2CKCNH2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971928-A1 | QUINOLINE-2(1H)-ONE AND DIHYDROQUINOLINE-2(1H)-ONE DERIVATIVES AS LIGANDS OF 5-HT, 5-HT2 AND 5-HT1-LIKE RECEPTORS | SANOFI-SYNTHELABO (FR) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042712-A1 | QUINOLINE-2(1H)-ONE AND DIHYDROQUINOLINE-2(1H)-ONE DERIVATIVES AS LIGANDS OF 5-HT, 5-HT2 AND 5-HT1-LIKE RECEPTORS | SANOFI-SYNTHELABO (FR) | 1998-10-01 | — | — | WO | disclosed |