SCHEMBL7406148

SCHEMBL7406148

CCCCCCCCCCCC(CC)O[C]=O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
SMPD1 P17405 3/20 0.37
GPR84 Q9NQS5 3/20 0.36
FDPS P14324 3/20 0.36
FFAR1 O14842 1/20 0.36
ZDHHC7 Q9NXF8 1/20 0.36
LMNA P02545 1/20 0.35
TRPM8 Q7Z2W7 3/20 0.35
LCK P06239 1/20 0.35
PPARD Q03181 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
DNM1 Q05193 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27473936 1.00 MAPT (0.39) MAPTSMPD1GPR84FDPSFFAR1
SCHEMBL3040226 1.00 MAPT (0.39) MAPTSMPD1GPR84FDPSFFAR1
SCHEMBL76605 1.00 MAPT (0.39) MAPTSMPD1GPR84FDPSFFAR1
SCHEMBL276890 0.98 MAPT (0.36) MAPTSMPD1GPR84FDPSFFAR1
SCHEMBL4164184 0.91 MAPT (0.42) MAPTSMPD1GPR84FDPSFFAR1
SCHEMBL7699553 0.91 MAPT (0.42) MAPTSMPD1GPR84FDPSFFAR1
SCHEMBL8371036 0.91 MAPT (0.42) MAPTSMPD1GPR84FDPSFFAR1
SCHEMBL4138235 0.91 TSHR (0.37) FDPSDNM1
SCHEMBL22342663 0.91 MAPT (0.42) MAPTSMPD1GPR84FDPSFFAR1
SCHEMBL9777154 0.89 MAPT (0.39) MAPTSMPD1GPR84FDPSFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941237-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-09-15 EP disclosed
EP-0854863-A1 ESTERS AND AMIDES AS PLA2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-29 EP disclosed
WO-1998022498-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-05-28 WO disclosed
WO-1997003951-A1 ESTERS AND AMIDES AS PLA2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-02-06 WO disclosed