Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.45 |
| ▸ | F10 | P00742 | 6/20 | 0.45 |
| ▸ | F7 | P08709 | 3/20 | 0.45 |
| ▸ | PLAU | P00749 | 5/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | PLG | P00747 | 4/20 | 0.40 |
| ▸ | PLAT | P00750 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | HPN | P05981 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405163 | 0.82 | F2 (0.53) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7397941 | 0.79 | F7 (0.50) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7406501 | 0.78 | F2 (0.53) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7403772 | 0.77 | F10 (0.47) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7510086 | 0.77 | F10 (0.45) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7408796 | 0.76 | F2 (0.44) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7409134 | 0.75 | F2 (0.55) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7406060 | 0.75 | F10 (0.46) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7403000 | 0.75 | F10 (0.58) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7410068 | 0.74 | F2 (0.49) | F2F10F7PLAUPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |