Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288664 | 1.00 | RNPEP (0.48) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL2412183 | 0.86 | RNPEP (0.55) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL15841629 | 0.84 | TP53 (0.43) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL6943835 | 0.82 | RNPEP (0.46) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL6943831 | 0.82 | RNPEP (0.46) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL15846727 | 0.82 | RNPEP (0.46) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL9515863 | 0.82 | RNPEP (0.46) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL2717757 | 0.81 | SLC1A3 (0.62) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL7384828 | 0.80 | SLC1A3 (0.45) | RNPEPSLC7A5SLC1A3SLC1A2TP53 | |
| SCHEMBL27731260 | 0.79 | RNPEP (0.48) | RNPEPSLC7A5SLC1A3SLC1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191150-B1 | METALLOPROTEASE INHIBITOR | GLAXO WELLCOME INC. | 2001-02-20 | — | — | US | disclosed |
| WO-2000012466-A1 | FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |