⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987312 | 0.71 | — | — | |
| SCHEMBL11794173 | 0.67 | HDAC6 (0.43) | — | |
| SCHEMBL8970885 | 0.65 | — | — | |
| SCHEMBL4110763 | 0.64 | P4HTM (0.38) | — | |
| SCHEMBL2881376 | 0.64 | — | — | |
| SCHEMBL3987514 | 0.64 | — | — | |
| SCHEMBL1515107 | 0.61 | — | — | |
| SCHEMBL1515333 | 0.61 | — | — | |
| SCHEMBL25060909 | 0.60 | GAA (0.50) | — | |
| SCHEMBL11845835 | 0.60 | HDAC1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960108-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998033788-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-08-06 | — | — | WO | disclosed |