Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401909 | 0.81 | KDM4E (0.58) | DRD4SLC6A2SLC6A4SLC6A3TMEM97 | |
| Hydrochloric Acid SCHEMBL7407347 | 0.80 | KDM4E (0.57) | DRD4SLC6A2SLC6A4SLC6A3TMEM97 | |
| SCHEMBL8807877 | 0.78 | DRD4 (0.85) | DRD4SLC6A2SLC6A4TMEM97SIGMAR1 | |
| SCHEMBL7398370 | 0.76 | MAOB (0.56) | SLC6A2SLC6A4SLC6A3TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7403805 | 0.76 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3TMEM97SIGMAR1 | |
| SCHEMBL7400101 | 0.76 | TMEM97 (0.70) | SLC6A2SLC6A4SLC6A3TMEM97SIGMAR1 | |
| SCHEMBL7397997 | 0.75 | TMEM97 (0.62) | SLC6A2SLC6A4SLC6A3TMEM97SIGMAR1 | |
| SCHEMBL3926715 | 0.75 | TMEM97 (0.62) | SLC6A2SLC6A4SLC6A3TMEM97SIGMAR1 | |
| SCHEMBL7406223 | 0.75 | SLC6A2 (0.57) | SLC6A2SLC6A4TMEM97SIGMAR1MAOB | |
| Hydrochloric Acid SCHEMBL7406109 | 0.75 | MAOB (0.55) | SLC6A2SLC6A4SLC6A3TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869792-A4 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0869792-A2 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023216-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |