Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 9/20 | 0.59 |
| ▸ | F10 | P00742 | 8/20 | 0.57 |
| ▸ | F2 | P00734 | 7/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19710439 | 0.79 | TSHR (0.74) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL3831539 | 0.78 | F10 (0.58) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL3832891 | 0.78 | KLKB1 (0.72) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL18622996 | 0.76 | KLKB1 (0.65) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL7395467 | 0.76 | F10 (0.60) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL18623001 | 0.75 | KLKB1 (0.66) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL18623002 | 0.75 | KLKB1 (0.66) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL3833307 | 0.75 | F10 (0.56) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL18623006 | 0.73 | KLKB1 (0.64) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL18623107 | 0.73 | KLKB1 (0.60) | KLKB1F10F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946508-A1 | NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS | Du Pont Pharmaceuticals Company (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028269-A1 | NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |