⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4435690 | 0.97 | — | — | |
| SCHEMBL8701984 | 0.97 | — | — | |
| SCHEMBL1461605 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL22117638 | 0.94 | — | — | |
| SCHEMBL727899 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL34474224 | 0.88 | — | — | |
| Formamide SCHEMBL28076360 | 0.86 | — | — | |
| SCHEMBL7773808 | 0.84 | — | — | |
| Nitric Acid SCHEMBL27678552 | 0.79 | MAPT (0.33) | — | |
| SCHEMBL3104689 | 0.78 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192696-A1 | SPIRO COMPOUNDS AS INHIBITORS OF KRAS | INCYTE CORPORATION | 2023-06-22 | — | — | US | claimed |
| US-11530218-B2 | Spiro compounds as inhibitors of KRAS | INCYTE CORPORATION (US) | 2022-12-20 | — | — | US | claimed |
| US-20210230162-A1 | SPIRO COMPOUNDS AS INHIBITORS OF KRAS | INCYTE CORPORATION | 2021-07-29 | — | — | US | claimed |
| WO-2021150613-A1 | SPIRO COMPOUNDS AS INHIBITORS OF KRAS | INCYTE CORPORATION (US) | 2021-07-29 | — | — | WO | claimed |
| CN-110168053-A | Liquid crystal aligning agent composition, method for manufacturing liquid crystal alignment film using same, and liquid crystal alignment film using same | 株式会社LG化学 | 2019-08-23 | — | — | CN | claimed |
| US-20190127413-A1 | Compositions and Methods for Non-Toxic Delivery of Antiprogestins | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2019-05-02 | — | — | US | claimed |
| CN-109312027-A | Method and hydrocarbon soluble salt-like hydride catalysts for hydrogen mediated, salt-like hydride initiated anionic chain transfer polymerization and polymer distribution compositions produced therefrom | 雅宝公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109069986-A | For separating CO from a mixed gaseous feed stream 2Membrane contactor comprising a composite membrane of a porous layer and a non-porous selective polymer layer | 挪威科技大学 | 2018-12-21 | — | — | CN | claimed |
| CN-108715579-A | A kind of 2-（α Hydroxy pentyls）The organic amine ester derivative drug of benzoic acid | 四川大学 | 2018-10-30 | — | — | CN | claimed |
| CN-108484880-A | The amine catalysis of epoxy resin is thiol-cured | 图茨技术股份有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-105980443-A | Amine Catalyzed Thiol Curing of Epoxy Resins | 卡尔蔡司斯马特光学有限公司 | 2016-09-28 | — | — | CN | claimed |
| EP-2550288-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | Repros Therapeutics Inc. (US) | 2013-01-30 | — | — | EP | claimed |
| US-20130018027-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | REPROS THERAPEUTICS INC. (US) | 2013-01-17 | — | — | US | claimed |
| CN-101511459-B | Amine aqueous solution for forming an active layer of polyamide reverse osmosis composite membrane, polyamide reverse osmosis composite membrane prepared thereby, and preparation method thereof | WOONGJIN COWAY CO LTD | 2012-08-08 | — | — | CN | claimed |
| CN-102227238-A | Color cosmetics containing random terpolymer | BASF SE | 2011-10-26 | — | — | CN | claimed |
| WO-2011119194-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | REPROS THERAPEUTICS INC. (US) | 2011-09-29 | — | — | WO | claimed |
| CN-102198368-A | Chemical compounds for the removal of carbon dioxide from gases | BABCOCK & WILCOX POWER GENERAT | 2011-09-28 | — | — | CN | claimed |
| CN-101677938-A | Sunscreen compositions comprising random terpolymers | BASF SE | 2010-03-24 | — | — | CN | claimed |
| CN-101511459-A | Amine aqueous solution for forming an active layer of polyamide reverse osmosis composite membrane, polyamide reverse osmosis composite membrane prepared thereby, and preparation method thereof | WOONGJIN COWAY CO LTD (KR) | 2009-08-19 | — | — | CN | claimed |
| CN-1980637-A | Liposomes for drug delivery | HERMES BIOSCIENCES INC (US) | 2007-06-13 | — | — | CN | claimed |