Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28973812 | 1.00 | MEN1 (0.43) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL7411935 | 1.00 | MEN1 (0.43) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL10981871 | 1.00 | MEN1 (0.43) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL29756463 | 0.89 | MEN1 (0.55) | MEN1KMT2APAK1FASNMAPT | |
| SCHEMBL7324242 | 0.89 | POLB (0.49) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL7410602 | 0.89 | POLB (0.49) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL23534110 | 0.88 | MEN1 (0.42) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL7411522 | 0.88 | MEN1 (0.42) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL7324438 | 0.88 | MEN1 (0.42) | MEN1KMT2APAK1FASNPOLB | |
| SCHEMBL29756609 | 0.88 | MEN1 (0.42) | MEN1KMT2APAK1FASNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031727-B1 | MEDICINAL COMPOSITIONS COMPRISING AS AN ACTIVE INGREDIENT SUBSTITUTED 1,4-BENZOQUINONES | Takeda Chemical Industries, Ltd. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4559177-A | HYPOTENSIVE, CARDIOTONIC AND ANTIPHYLATIC AGENTS; ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-17 | — | — | US | disclosed |
| US-4495104-A | PHARMACEUTICAL COMPOUNDS EFFECTIVE AGAINST HEART FAILURE, DERIODONTAL DISEASE, DIABETES; HYPOTENSIVE AND ANTIANAPHYLACTIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-01-22 | — | — | US | disclosed |
| EP-0021841-B1 | 2,3-DIALKOXY-1,4-QUINONE DERIVATIVES; METHOD OF PRODUCING 1,4-QUINONE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4436753-A | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-03-13 | — | — | US | disclosed |
| EP-0031727-A2 | Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones | Takeda Chemical Industries, Ltd. (JP) | 1981-07-08 | — | — | EP | disclosed |
| EP-0021841-A2 | 2,3-Dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |