Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.36 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409739 | 1.00 | ACE (0.47) | ACELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL7410505 | 0.93 | ACE (0.51) | ACELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL7410513 | 0.93 | ACE (0.51) | ACELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL7408838 | 0.93 | ACE (0.53) | ACELMNASMN1; SMN2TACR1SLC12A2 | |
| SCHEMBL7408843 | 0.93 | ACE (0.53) | ACELMNASMN1; SMN2TACR1SLC12A2 | |
| SCHEMBL7414691 | 0.90 | ACE (0.42) | ACELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL7414703 | 0.90 | ACE (0.42) | ACELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL7418557 | 0.88 | ACE (0.52) | ACEPOLBTDP1L3MBTL1TACR1 | |
| SCHEMBL7418553 | 0.88 | ACE (0.52) | ACEPOLBTDP1L3MBTL1TACR1 | |
| SCHEMBL10991046 | 0.88 | ACE (0.46) | ACELMNAPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885293-A | CARBOXYALKYL DIPEPTIDES | SCHERING CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| US-4826816-A | Antihypertensive compounds | SCHERING CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| US-4556655-A | TREATMENT OF CARDIOVASCULAR DISORDERS AND GLAUCOMA | SCHERING CORPORATION (US) | 1985-12-03 | — | — | US | disclosed |