Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405101 | 0.90 | PREP (0.54) | — | |
| SCHEMBL7401667 | 0.85 | ELANE (0.58) | ELANE | |
| SCHEMBL7511361 | 0.84 | ELANE (0.60) | ELANEF2CTSG | |
| SCHEMBL7511367 | 0.84 | ELANE (0.60) | ELANEF2CTSG | |
| SCHEMBL10170415 | 0.83 | ELANE (0.50) | ELANEF2CTSG | |
| SCHEMBL2437607 | 0.82 | ELANE (0.51) | ELANE | |
| SCHEMBL12299749 | 0.82 | ELANE (0.51) | ELANE | |
| SCHEMBL8131836 | 0.82 | ELANE (0.49) | ELANEF2CTSG | |
| SCHEMBL2632237 | 0.82 | ELANE (0.49) | ELANEF2CTSG | |
| SCHEMBL34466304 | 0.81 | ACE2 (0.49) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015454-A1 | METHOD OF INHIBITING SERINE PROTEASE ENZYMES | GLAXO GROUP LIMITED (GB) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000018770-A1 | PYRROLOPYRROLONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXO GROUP LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |
| EP-0973775-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999012932-A1 | METHOD OF INHIBITING SERINE PROTEASE ENZYMES | GLAXO GROUP LIMITED (GB) | 1999-03-18 | — | — | WO | disclosed |
| WO-1998043975-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |