Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.71 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.64 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | HTR7 | P34969 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526687 | 0.89 | PDE10A (0.69) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL30176852 | 0.86 | PARP1 (0.73) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL16404338 | 0.85 | PDE10A (0.84) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL1586541 | 0.85 | PARP1 (0.91) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL30176973 | 0.84 | PARP1 (0.89) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL6795539 | 0.84 | PARP1 (0.69) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL4852668 | 0.84 | PARP1 (0.69) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL30176861 | 0.84 | PARP1 (0.89) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL22857122 | 0.84 | PARP1 (0.89) | PARP1PDE10APARP2TNKS2KMT2A | |
| SCHEMBL14621928 | 0.84 | PARP1 (0.89) | PARP1PDE10APARP2TNKS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200072-A2 | METHOD OF TREATING PSYCHOTIC DISORDERS | Solvay Pharmaceuticals B.V. (NL) | 2002-05-02 | — | — | EP | disclosed |
| WO-2000069424-A2 | METHOD OF TREATING PSYCHOTIC DISORDERS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2000-11-23 | — | — | WO | disclosed |