Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.62 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410542 | 0.91 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8318709 | 0.91 | AVPR2 (0.54) | AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7414353 | 0.90 | AVPR2 (0.75) | AVPR2AVPR1A | |
| SCHEMBL7417248 | 0.88 | AVPR2 (0.60) | AVPR2AVPR1A | |
| SCHEMBL7409772 | 0.88 | AVPR2 (0.63) | AVPR2AVPR1A | |
| SCHEMBL7418434 | 0.85 | AVPR2 (0.64) | AVPR2AVPR1A | |
| SCHEMBL7331708 | 0.84 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL7339924 | 0.83 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL7416367 | 0.83 | AVPR2 (0.53) | AVPR2AVPR1A | |
| SCHEMBL7410950 | 0.82 | AVPR2 (0.53) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843944-A | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-01 | — | — | US | claimed |
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5854237-A | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-29 | — | — | US | disclosed |
| US-5843944-A | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5733905-A | CONGESTIVE HEART FAILURE; KIDNEY DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1998-03-31 | — | — | US | disclosed |