Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10491910 | 0.83 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL10491904 | 0.83 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL10491912 | 0.83 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL13785322 | 0.80 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3ALDH1A1MEN1 | |
| Oxalic Acid SCHEMBL10491881 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| Oxalic Acid SCHEMBL10491878 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| Oxalic Acid SCHEMBL10491884 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL12193236 | 0.78 | FFAR1 (0.65) | FFAR1 | |
| SCHEMBL12193237 | 0.78 | FFAR1 (0.65) | FFAR1 | |
| SCHEMBL7404547 | 0.77 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |
| EP-1121353-A1 | BENZAZINE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON GROUP S.p.A. (IT) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021947-A1 | BENZAZINE DERIVATIVES AS PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON GROUP S.P.A. (IT) | 2000-04-20 | — | — | WO | disclosed |