Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.63 |
| ▸ | UTS2R | Q9UKP6 | 11/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411042 | 0.92 | UTS2R (0.62) | MCHR1UTS2RDRD4 | |
| SCHEMBL7403975 | 0.91 | DRD4 (0.66) | MCHR1UTS2RDRD4 | |
| SCHEMBL7412275 | 0.90 | UTS2R (0.62) | MCHR1UTS2RDRD4 | |
| SCHEMBL7402864 | 0.89 | UTS2R (0.61) | MCHR1UTS2RDRD4 | |
| SCHEMBL7412018 | 0.89 | UTS2R (0.64) | UTS2RDRD4 | |
| SCHEMBL7407746 | 0.89 | UTS2R (0.64) | UTS2RDRD4 | |
| SCHEMBL7412384 | 0.89 | UTS2R (0.64) | UTS2RDRD4 | |
| SCHEMBL7409679 | 0.88 | UTS2R (0.63) | MCHR1UTS2R | |
| SCHEMBL7409331 | 0.88 | UTS2R (0.64) | UTS2RDRD4 | |
| SCHEMBL7411577 | 0.88 | DRD4 (0.64) | MCHR1UTS2RDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369077-B1 | OSTEOPOROSIS, PERIODONTITIS, AND ARTHRITIS | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | claimed |
| EP-0991753-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-07-11 | — | — | EP | claimed |
| EP-0991753-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | claimed |
| WO-1998050534-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |
| US-6369077-B1 | OSTEOPOROSIS, PERIODONTITIS, AND ARTHRITIS | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | disclosed |
| EP-0991753-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0991753-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998050534-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |