Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 12/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412664 | 0.92 | UTS2R (0.61) | UTS2RCHRM2CHRM3DRD4 | |
| SCHEMBL7412018 | 0.90 | UTS2R (0.64) | UTS2RDRD4CTSK | |
| SCHEMBL7412384 | 0.90 | UTS2R (0.64) | UTS2RDRD4CTSK | |
| SCHEMBL7407746 | 0.90 | UTS2R (0.64) | UTS2RDRD4CTSK | |
| SCHEMBL7411042 | 0.90 | UTS2R (0.62) | UTS2RMCHR1DRD4CTSK | |
| SCHEMBL7411128 | 0.88 | UTS2R (0.56) | UTS2RMCHR1DRD4 | |
| SCHEMBL7410726 | 0.87 | UTS2R (0.58) | UTS2RMCHR1DRD4 | |
| SCHEMBL7411031 | 0.86 | DRD4 (0.67) | UTS2RCHRM2CHRM3MCHR1DRD4 | |
| SCHEMBL7409331 | 0.86 | UTS2R (0.64) | UTS2RDRD4 | |
| SCHEMBL7411577 | 0.86 | DRD4 (0.64) | UTS2RMCHR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369077-B1 | OSTEOPOROSIS, PERIODONTITIS, AND ARTHRITIS | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | claimed |
| EP-0991753-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-07-11 | — | — | EP | claimed |
| EP-0991753-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | claimed |
| WO-1998050534-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |
| US-6369077-B1 | OSTEOPOROSIS, PERIODONTITIS, AND ARTHRITIS | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | disclosed |
| EP-0991753-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0991753-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998050534-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |