Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.63 |
| ▸ | PDE4A | P27815 | 9/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575456 | 0.89 | CA12 (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1031663 | 0.89 | CA12 (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7389578 | 0.84 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29670247 | 0.83 | TSHR (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15596058 | 0.83 | TSHR (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL12508471 | 0.83 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2040708 | 0.81 | CA12 (0.72) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4269812 | 0.81 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3377412 | 0.81 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL20428527 | 0.81 | CA12 (0.55) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995027692-A1 | SUBTITUTED BIPHENYL TNF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-19 | — | — | WO | disclosed |