Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.55 |
| ▸ | HTR6 | P50406 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7404475 | 0.99 | KDM4E (0.60) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| SCHEMBL7413263 | 0.89 | PTGDR2 (0.56) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| SCHEMBL7409304 | 0.89 | PTGDR2 (0.55) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| Hydrochloric Acid SCHEMBL7412317 | 0.89 | PTGDR2 (0.55) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| SCHEMBL27989288 | 0.86 | KDM4E (0.59) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| SCHEMBL2313013 | 0.86 | KDM4E (0.59) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| SCHEMBL7409341 | 0.85 | PTGDR2 (0.72) | KDM4EPTGDR2TBXA2RPTGDRHTR6 | |
| SCHEMBL7411114 | 0.85 | PTGDR2 (0.54) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| Bromide SCHEMBL2430564 | 0.85 | KDM4E (0.58) | KDM4ELMNAPTGDR2TBXA2RPTGDR | |
| Hydrochloric Acid SCHEMBL27883098 | 0.85 | KDM4E (0.61) | KDM4ELMNAPTGDR2TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | claimed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |