Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.63 |
| ▸ | F10 | P00742 | 4/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102588 | 1.00 | F2 (0.63) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7413543 | 0.96 | F2 (0.63) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7412760 | 0.96 | F2 (0.63) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7408749 | 0.95 | F2 (0.64) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7409419 | 0.94 | F2 (0.72) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7415709 | 0.94 | F2 (0.62) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7423452 | 0.94 | F2 (0.62) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7488074 | 0.94 | F2 (0.65) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7418085 | 0.90 | F2 (0.69) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7100450 | 0.89 | F2 (0.66) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |