Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 10/20 | 0.45 |
| ▸ | F3 | P13726 | 10/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.45 |
| ▸ | F2 | P00734 | 7/20 | 0.45 |
| ▸ | F10 | P00742 | 9/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422146 | 0.90 | F10 (0.39) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL7419716 | 0.87 | F7 (0.62) | F7F3PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7416747 | 0.86 | F7 (0.61) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL7413994 | 0.84 | HSP90AA1 (0.38) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL5882369 | 0.83 | KCNA5 (0.46) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL5882560 | 0.81 | PRSS1 (0.61) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL5883391 | 0.80 | PRSS1 (0.50) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL5883399 | 0.80 | PRSS1 (0.50) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL5882824 | 0.79 | F7 (0.47) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL5882773 | 0.79 | F7 (0.53) | F7F3PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |