Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12987536 | 0.80 | BTK (0.37) | GAAEPHX1BTK | |
| SCHEMBL2557560 | 0.80 | BTK (0.37) | GAAEPHX1BTK | |
| SCHEMBL17419373 | 0.80 | GAA (0.32) | GAAEPHX1 | |
| SCHEMBL741147 | 0.80 | GAA (0.32) | GAAEPHX1 | |
| SCHEMBL8796961 | 0.80 | GAA (0.32) | GAAEPHX1 | |
| SCHEMBL16061017 | 0.75 | BTK (0.38) | BTK | |
| SCHEMBL27555433 | 0.74 | MAPK1 (0.31) | BTK | |
| SCHEMBL3892591 | 0.74 | KDM1A (0.32) | BTK | |
| SCHEMBL27938773 | 0.70 | MAPK1 (0.33) | — | |
| SCHEMBL21064068 | 0.70 | GAA (0.32) | GAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-B1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |