Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371001 | 0.90 | F2 (0.69) | F2HPGDALPL | |
| SCHEMBL7379123 | 0.89 | F2 (0.58) | F2HPGDLMNA | |
| SCHEMBL7374256 | 0.88 | F2 (0.59) | F2HPGDLMNA | |
| SCHEMBL8649210 | 0.84 | F2 (0.60) | F2HPGDLMNA | |
| SCHEMBL7409794 | 0.84 | F2 (0.63) | F2HPGDLMNA | |
| SCHEMBL7373990 | 0.83 | F2 (0.62) | F2HPGDALPLLMNASMN1; SMN2 | |
| SCHEMBL8664965 | 0.82 | F2 (0.62) | F2HPGDALPL | |
| SCHEMBL7358686 | 0.81 | F2 (0.57) | F2HPGDALPLLMNASMN1; SMN2 | |
| SCHEMBL8648601 | 0.81 | F2 (0.59) | F2HPGDLMNA | |
| SCHEMBL8650605 | 0.81 | F2 (0.59) | F2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778829-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006832-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-03-07 | — | — | WO | disclosed |