Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372654 | 0.96 | F2 (0.54) | F2PSMB5HPGDGAAPER2 | |
| SCHEMBL7373800 | 0.94 | F2 (0.54) | F2PSMB5HPGDTP53MAPT | |
| SCHEMBL7374410 | 0.92 | F2 (0.53) | F2PSMB5HPGDMMP9MMP13 | |
| SCHEMBL7409794 | 0.92 | F2 (0.63) | F2HPGDGAALMNAHTT | |
| SCHEMBL7372831 | 0.91 | F2 (0.54) | F2PSMB5HPGDPER2CRY1 | |
| SCHEMBL8648794 | 0.90 | F2 (0.51) | F2PSMB5HPGDTP53MAPT | |
| SCHEMBL8652523 | 0.89 | F2 (0.54) | F2HPGD | |
| SCHEMBL8648601 | 0.87 | F2 (0.59) | F2HPGDGAALMNAHTT | |
| SCHEMBL8649210 | 0.86 | F2 (0.60) | F2HPGDGAALMNAHTT | |
| SCHEMBL8646156 | 0.86 | F2 (0.47) | F2HPGDLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795892-A | ANTICOAGULANTS | BOEHRINGER MANNEIM GMBH (DE) | 1998-08-18 | — | — | US | disclosed |
| EP-0778829-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006832-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-03-07 | — | — | WO | disclosed |