Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23823660 | 0.86 | CYP1A2 (0.64) | CYP1A2TDP1PIK3CDDRD3HRH3 | |
| SCHEMBL378022 | 0.80 | CYP1A2 (0.56) | CYP1A2TDP1PIK3CDDRD3HRH3 | |
| SCHEMBL2619225 | 0.80 | CYP1A2 (0.56) | CYP1A2TDP1PIK3CDDRD3HRH3 | |
| SCHEMBL297533 | 0.80 | CYP1A2 (0.56) | CYP1A2TDP1PIK3CDDRD3HRH3 | |
| SCHEMBL7413694 | 0.79 | DRD3 (0.49) | DRD3ALDH1A1HTR7 | |
| Hydrochloric Acid SCHEMBL20261838 | 0.78 | CYP1A2 (0.54) | CYP1A2TDP1PIK3CDDRD3HRH3 | |
| SCHEMBL296688 | 0.78 | CYP1A2 (0.54) | CYP1A2TDP1PIK3CDDRD3HRH3 | |
| SCHEMBL20961902 | 0.78 | CYP1A2 (0.54) | CYP1A2TDP1PIK3CDDRD3HRH3 | |
| SCHEMBL13589531 | 0.78 | CYP1A2 (0.54) | CYP1A2TDP1PIK3CDDRD3HRH3 | |
| SCHEMBL298010 | 0.78 | CYP1A2 (0.54) | CYP1A2TDP1PIK3CDDRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273976-A | Ocular hypotensive agents | SANKYO COMPANY, LIMITED (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5175161-A | Treatment of glaucoma | SANKYO COMPANY, LIMITED (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0391721-A2 | Ocular hypotensive agents | Sankyo Company Limited (JP) | 1990-10-10 | — | — | EP | disclosed |