Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.59 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | HTR7 | P34969 | 10/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | HTR5A | P47898 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455554 | 0.86 | CHRM3 (0.59) | HTR2CHTR2AHTR7CHRM3CHRM2 | |
| Gaboxadol SCHEMBL5533785 | 0.86 | CHRM3 (0.46) | HTR2CHTR2AHTR7HTR2BHTR3A | |
| Gaboxadol SCHEMBL247815 | 0.86 | CHRM3 (0.46) | HTR2CHTR2AHTR7HTR2BHTR3A | |
| Bromide SCHEMBL10652839 | 0.84 | CHRM3 (0.57) | HTR2CHTR2AHTR7CHRM3CHRM2 | |
| Gaboxadol SCHEMBL23851948 | 0.84 | CHRM3 (0.45) | HTR2CHTR2AHTR7HTR2BHTR3A | |
| Gaboxadol SCHEMBL3983776 | 0.84 | CHRM3 (0.45) | HTR2CHTR2AHTR7HTR2BHTR3A | |
| Gaboxadol SCHEMBL3979055 | 0.84 | CHRM3 (0.45) | HTR2CHTR2AHTR7HTR2BHTR3A | |
| Gaboxadol SCHEMBL567225 | 0.84 | CHRM3 (0.49) | HTR2CHTR2AHTR7CHRM3CHRM2 | |
| Gaboxadol SCHEMBL1403323 | 0.84 | CHRM3 (0.45) | HTR2CHTR2AHTR7HTR2BHTR3A | |
| Gaboxadol SCHEMBL3980688 | 0.84 | CHRM3 (0.45) | HTR2CHTR2AHTR7HTR2BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761083-B | 5-HT for treating depression 2A Agonists | 罗福拉公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-3962601-B1 | 5-HT2A AGONISTS FOR USE IN TREATMENT OF DEPRESSION | Lophora ApS (DK) | 2023-05-31 | — | — | EP | disclosed |
| CN-114761083-A | 5-HT for the treatment of depression2AAgonists | 罗福拉公司 | 2022-07-15 | — | — | CN | disclosed |
| EP-0350051-A1 | Thaz derivatives for enhancemet of cerebral function | Bristol-Myers Squibb Company (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4859666-A | THAZ derivatives for enhancement of cerebral function | BRISTOL-MYERS COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0000338-B1 | ISOXAZOLO(5,4-C)PYRIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | H.Lundbeck & Co., A/S (DK) | 1981-11-25 | — | — | EP | disclosed |
| US-4301287-A | FOR TREATMENT OF PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | H. LUNDBECK & CO. A/S (DK) | 1981-11-17 | — | — | US | disclosed |
| US-4278676-A | NERVOUS SYSTEM DISORDERS, CYCLIZATION, HYDROLYSIS | H. LUNDBECK & CO. A/S (DK) | 1981-07-14 | — | — | US | disclosed |
| EP-0000338-A2 | Isoxazolo(5,4-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them | H.Lundbeck & Co., A/S (DK) | 1979-01-24 | — | — | EP | disclosed |