SCHEMBL7412990

SCHEMBL7412990

CC(C)OC(=O)N(C)C(C)(C(=O)N1CCCC1)c1ccc2c(c1)nc(C(N)c1ccc(C(=N)NC(=O)OCC(Cl)(Cl)Cl)cc1)n2C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2 P00734 9/20 0.39
F10 P00742 7/20 0.39
PLG P00747 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7415568 0.93 F2 (0.38) F2F10PLG
SCHEMBL7415705 0.89 F2 (0.38) F2F10PLG
SCHEMBL7423449 0.89 F2 (0.38) F2F10PLG
SCHEMBL7408713 0.88 F2 (0.39) F2F10PLG
SCHEMBL7418083 0.87 F2 (0.41) F2F10PLG
SCHEMBL7488072 0.84 F2 (0.39) F2F10PLG
SCHEMBL7417231 0.84 F2 (0.38) F2F10PLG
SCHEMBL7408746 0.83 F2 (0.40) F2F10PLG
SCHEMBL7410854 0.83 F2 (0.40) F2F10PLG
SCHEMBL7413698 0.83 F2 (0.39) F2F10PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095025-B1 BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA (DE) 2002-12-11 EP disclosed
US-6248770-B1 CARDIOVASCULAR DISORDERS BOEHRINGER INGELHEIM PHARMA KG (DE) 2001-06-19 US disclosed