Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.55 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095305 | 0.92 | ADORA2A (0.66) | ADORA2AADORA2BCYP2D6CYP2C9TSHR | |
| SCHEMBL7413754 | 0.91 | ADORA1 (0.56) | ADORA2AADORA2BCYP2D6CYP2C9TSHR | |
| SCHEMBL7417571 | 0.89 | ADORA2A (0.63) | ADORA2AADORA2BCYP2D6CYP2C9TSHR | |
| SCHEMBL5170154 | 0.88 | ADORA2A (0.57) | ADORA2AADORA2BCYP2D6CYP2C9TSHR | |
| SCHEMBL7424205 | 0.87 | ADORA2A (0.55) | ADORA2AADORA2BCYP2D6CYP2C9TSHR | |
| SCHEMBL10709093 | 0.85 | ADORA1 (0.62) | ADORA2AADORA2BADORA1P2RY1P2RY2 | |
| SCHEMBL7408724 | 0.83 | ADORA2A (0.55) | ADORA2AADORA2BCYP2D6CYP2C9TSHR | |
| SCHEMBL3450680 | 0.83 | ADORA1 (0.68) | ADORA2AADORA2BADORA1P2RY1P2RY2 | |
| SCHEMBL10707455 | 0.83 | ADORA1 (0.61) | ADORA2AADORA2BADORA1P2RY1P2RY2 | |
| SCHEMBL7416653 | 0.80 | ADORA1 (0.57) | ADORA2AADORA2BADORA1P2RY1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | claimed |