Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.49 |
| ▸ | F2 | P00734 | 10/20 | 0.49 |
| ▸ | PLG | P00747 | 6/20 | 0.47 |
| ▸ | PROC | P04070 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409263 | 0.86 | F10 (0.42) | F10PRSS1F2PLGPROC | |
| SCHEMBL7407161 | 0.85 | F10 (0.48) | F10PRSS1F2PLGPROC | |
| SCHEMBL7412543 | 0.85 | F10 (0.36) | F10PRSS1F2PLGPROC | |
| SCHEMBL7417433 | 0.85 | F10 (0.49) | F10PRSS1F2PLGPROC | |
| SCHEMBL7411495 | 0.84 | F10 (0.69) | F10PRSS1F2PLGPROC | |
| SCHEMBL7515067 | 0.84 | F10 (0.69) | F10PRSS1F2PLGPROC | |
| SCHEMBL7410111 | 0.84 | F10 (0.69) | F10PRSS1F2PLGPROC | |
| SCHEMBL7414989 | 0.84 | F10 (0.46) | F10PRSS1F2PLGPROC | |
| SCHEMBL7530822 | 0.84 | F10 (0.52) | F10PRSS1F2PLGPROC | |
| SCHEMBL7409995 | 0.83 | F10 (0.53) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068191-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999050257-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | disclosed |