Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.55 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 19/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 19/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PLD2 | O14939 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | C5 | P01031 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7413891 | 1.00 | ESR1 (0.68) | ESR1ESR2F2MEN1PLD2 | |
| SCHEMBL7408397 | 0.98 | ESR1 (0.70) | ESR1ESR2F2MEN1PLD2 | |
| SCHEMBL7408395 | 0.98 | ESR1 (0.70) | ESR1ESR2F2MEN1PLD2 | |
| SCHEMBL7414728 | 0.98 | ESR1 (0.70) | ESR1ESR2F2MEN1PLD2 | |
| Oxalic Acid SCHEMBL7414313 | 0.87 | F2 (0.51) | ESR1ESR2F2 | |
| Oxalic Acid SCHEMBL7414182 | 0.87 | F2 (0.51) | ESR1ESR2F2 | |
| Oxalic Acid SCHEMBL7414178 | 0.87 | F2 (0.51) | ESR1ESR2F2 | |
| SCHEMBL7768315 | 0.87 | ESR1 (0.76) | ESR1ESR2F2MEN1PLD2 | |
| SCHEMBL7768313 | 0.87 | ESR1 (0.76) | ESR1ESR2F2MEN1PLD2 | |
| SCHEMBL7773970 | 0.87 | ESR1 (0.76) | ESR1ESR2F2MEN1PLD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |