Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122326 | 0.94 | CHRM2 (0.38) | CHRM2CHRM1CHRM3CHRM4MAPK1 | |
| SCHEMBL4830125 | 0.85 | CHRM1 (0.47) | CHRM2CHRM1CHRM3CHRM4ALDH1A1 | |
| SCHEMBL3745563 | 0.81 | MAPK1 (0.48) | CHRM1CHRM4MAPK1ALDH1A1POLB | |
| SCHEMBL17101473 | 0.76 | MAPK1 (0.40) | CHRM2CHRM1CHRM3CHRM4MAPK1 | |
| SCHEMBL857819 | 0.75 | CHRM1 (0.38) | CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL29461904 | 0.75 | MAPK1 (0.42) | CHRM1MAPK1ALDH1A1POLB | |
| SCHEMBL156133 | 0.74 | CHRM2 (0.56) | CHRM2CHRM1CHRM3MAPK1 | |
| SCHEMBL12875999 | 0.74 | CHRM2 (0.56) | CHRM2CHRM1CHRM3MAPK1 | |
| SCHEMBL15618675 | 0.74 | CHRM1 (0.42) | CHRM2CHRM1CHRM3CHRM4MAPK1 | |
| SCHEMBL31694645 | 0.74 | MAPK1 (0.52) | CHRM2CHRM1CHRM3CHRM4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250537-A | Treating psychoses | SCIOS NOVA INC. (US) | 1993-10-05 | — | — | US | disclosed |