Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6926557 | 0.99 | PLAU (0.72) | PLAU | |
| Bromide SCHEMBL6924419 | 0.89 | PLAU (0.62) | PLAU | |
| SCHEMBL7388888 | 0.89 | PLAU (0.75) | PLAU | |
| Bromide SCHEMBL6925531 | 0.89 | PLAU (0.73) | PLAU | |
| Bromide SCHEMBL6927195 | 0.89 | PLAU (0.74) | PLAU | |
| Bromide SCHEMBL6924905 | 0.85 | PLAU (0.62) | PLAU | |
| Bromide SCHEMBL6925461 | 0.84 | PLAU (0.72) | PLAU | |
| SCHEMBL6921325 | 0.84 | PLAU (1.00) | PLAU | |
| Hydrochloric Acid SCHEMBL6926896 | 0.84 | PLAU (0.98) | PLAU | |
| Bromide SCHEMBL6927341 | 0.83 | PLAU (0.73) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150979-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047578-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-08-17 | — | — | WO | disclosed |