Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.66 |
| ▸ | HTR2A | P28223 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273073 | 0.86 | HTR2C (0.49) | HTR2CHTR2AMAPTNPC1RAB9A | |
| SCHEMBL7474827 | 0.83 | HTR2C (0.58) | HTR2CHTR2AMAPTNPC1RAB9A | |
| SCHEMBL7420874 | 0.81 | MAPT (0.59) | HTR2CHTR2AMAPTNPC1RAB9A | |
| SCHEMBL7417398 | 0.81 | HTR2C (1.00) | HTR2CHTR2AMAPTNPC1RAB9A | |
| SCHEMBL7469872 | 0.81 | HTR2C (0.89) | HTR2CHTR2AMAPTNPC1RAB9A | |
| SCHEMBL7419042 | 0.79 | HTR2C (1.00) | HTR2CHTR2AMAPTNPC1RAB9A | |
| SCHEMBL29369443 | 0.78 | HTR2C (1.00) | HTR2CHTR2AMAPTNPC1RAB9A | |
| SCHEMBL1459242 | 0.78 | HTR2C (1.00) | HTR2CHTR2AMAPTNPC1RAB9A | |
| SCHEMBL29462346 | 0.78 | HTR2C (1.00) | HTR2CHTR2AMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL10321748 | 0.77 | MAPT (1.00) | HTR2CHTR2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004533-A1 | CONDENSED INDOLE DERIVATIVES AS 5HT2C AND 5HT2B ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-03-03 | — | — | WO | disclosed |