Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.58 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.52 |
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416263 | 0.94 | ADORA1 (0.58) | ADORA1TRDMT1NNMTDNPH1PRKAB2 | |
| SCHEMBL7416653 | 0.87 | ADORA1 (0.57) | ADORA1NNMTDNPH1PRKAB2TRPM2 | |
| SCHEMBL5170154 | 0.87 | ADORA2A (0.57) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL3450680 | 0.82 | ADORA1 (0.68) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL7408724 | 0.82 | ADORA2A (0.55) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL10707455 | 0.82 | ADORA1 (0.61) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL10709093 | 0.81 | ADORA1 (0.62) | ADORA1TRDMT1DNPH1PRKAB2TRPM2 | |
| SCHEMBL10712349 | 0.81 | ADORA1 (0.62) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL7413754 | 0.81 | ADORA1 (0.56) | ADORA1NNMTDNPH1PRKAB2TRPM2 | |
| SCHEMBL10709852 | 0.81 | ADORA1 (0.59) | ADORA1DNPH1PRKAB2TRPM2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | claimed |