Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.58 |
| ▸ | F10 | P00742 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451660 | 1.00 | F2 (0.58) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7101562 | 0.89 | F2 (0.52) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7412689 | 0.85 | F2 (0.56) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL4442309 | 0.85 | F2 (0.59) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL4442315 | 0.85 | F2 (0.59) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL4451687 | 0.84 | F2 (0.64) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL4451691 | 0.84 | F2 (0.64) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7415304 | 0.84 | F2 (0.59) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7096709 | 0.83 | F2 (0.58) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7674059 | 0.83 | F2 (0.41) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |