Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.77 |
| ▸ | F2 | P00734 | 13/20 | 0.77 |
| ▸ | PLG | P00747 | 1/20 | 0.60 |
| ▸ | PROC | P04070 | 1/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2329182 | 0.96 | F10 (0.73) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7422663 | 0.94 | F10 (0.79) | F10F2PLGPROCPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7420490 | 0.92 | F10 (0.77) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7421936 | 0.92 | F10 (0.80) | F10F2PLGPROCPRSS1 | |
| SCHEMBL27493515 | 0.91 | F10 (0.74) | F10F2PLGPROCPRSS1 | |
| Trifluoroacetic Acid SCHEMBL2331116 | 0.91 | F10 (0.74) | F10F2PLGPROCPRSS1 | |
| Trifluoroacetic Acid SCHEMBL2326242 | 0.90 | F10 (0.75) | F10F2PLGPROCPRSS1 | |
| Trifluoroacetic Acid SCHEMBL2360098 | 0.89 | F10 (0.73) | F10F2PLGPROCPRSS1 | |
| Trifluoroacetic Acid SCHEMBL2326406 | 0.89 | F10 (0.75) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7419114 | 0.88 | F10 (0.59) | F10F2PLGPROCPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0853618-A4 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0853618-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |