Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.64 |
| ▸ | F10 | P00742 | 4/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418085 | 0.95 | F2 (0.69) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7412992 | 0.93 | F2 (0.63) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7488074 | 0.92 | F2 (0.65) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7417234 | 0.91 | F2 (0.64) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7413543 | 0.90 | F2 (0.63) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7412760 | 0.90 | F2 (0.63) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7413700 | 0.90 | F2 (0.64) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7099689 | 0.90 | F2 (0.67) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7413418 | 0.89 | F2 (0.70) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7416848 | 0.89 | F2 (0.68) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171437-A1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | Syngenta Limited (GB) | 2002-01-16 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |
| WO-2000063207-A1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | SYNGENTA LIMITED (GB) | 2000-10-26 | — | — | WO | disclosed |