Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.61 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.61 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 7/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | CPA3 | P15088 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540327 | 1.00 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| SCHEMBL5511480 | 0.86 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| SCHEMBL883357 | 0.86 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL4755513 | 0.85 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL7289849 | 0.85 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL2919214 | 0.85 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL305323 | 0.85 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| SCHEMBL24252143 | 0.84 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| SCHEMBL8333821 | 0.84 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1CYP1A2ACE | |
| SCHEMBL5708390 | 0.84 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1CYP1A2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115079-B2 | NDM inhibitor | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140221330-A1 | NDM INHIBITOR | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-5039664-A | Hypotensive agent | MERCK & CO., INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5037807-A | Hypotensive agents; for treatment of congestive heart failure | MERCK & CO., INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4839357-A | TREATMENT OF HYPERTENSION, CONGESTIVE HEART FAILURE | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0278158-A2 | Renin inhibitors containing phenylalanyl-histidine replacements | MERCK & CO. INC. (US) | 1988-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221330-A1 | NDM INHIBITOR | MGAM, NQO1, NQO2 | SLC1A3 4773/4885SLC1A2 4692/4885SLC1A1 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.