Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.40 |
| ▸ | F10 | P00742 | 7/20 | 0.40 |
| ▸ | PLG | P00747 | 3/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415480 | 1.00 | F2 (0.40) | F2F10PLGSIRT2CNR1 | |
| SCHEMBL7421013 | 0.96 | F2 (0.39) | F2F10PLGSIRT2CNR1 | |
| SCHEMBL7417194 | 0.96 | F2 (0.39) | F2F10PLGSIRT2CNR1 | |
| SCHEMBL7418432 | 0.94 | F2 (0.42) | F2F10PLGSIRT2PRSS1 | |
| SCHEMBL7414147 | 0.93 | F2 (0.40) | F2F10PLGCNR1PRSS1 | |
| SCHEMBL7414458 | 0.91 | F2 (0.40) | F2F10PLGSIRT2PRSS1 | |
| SCHEMBL7416312 | 0.91 | F2 (0.40) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7415358 | 0.90 | F2 (0.42) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7416666 | 0.86 | F2 (0.38) | F2F10PLGALDH1A1MAPT | |
| SCHEMBL7414747 | 0.84 | F2 (0.37) | F2F10PLGALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |