Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7416562

COc1ccc2ccc(S(=O)(=O)N[C@H]3CCN(Cc4csc5ccnc(O)c45)C3=O)cc2c1.O=C(O)C(F)(F)F

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 16/20 0.58
F2 P00734 7/20 0.58
PLG P00747 1/20 0.55
PLAT P00750 1/20 0.55
PROC P04070 1/20 0.55
PRSS1 P07477 1/20 0.55
KLK6 Q92876 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7383877 1.00 F10 (0.58) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7536982 0.93 F10 (0.62) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7540782 0.93 F10 (0.62) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7370369 0.89 F10 (0.58) F10F2PLGPLATPROC
SCHEMBL7544799 0.86 F10 (0.62) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7538076 0.85 F10 (0.64) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL8428287 0.81 F10 (0.69) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7219109 0.81 F10 (0.71) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7444305 0.81 F10 (0.71) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL8428190 0.80 F10 (0.66) F10F2PLGPLATPROC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMACEUTICALS PRODUCTS INC. 2002-01-31 US disclosed
EP-0944386-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2001-04-11 EP disclosed
EP-0944386-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-09-29 EP disclosed
WO-1998025611-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds STS, ARSA, F12 F10 20/4885F2 11/4885PLG 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.