Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 4/20 | 0.59 |
| ▸ | XIAP | P98170 | 3/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132571 | 1.00 | NPY1R (0.59) | NPY1RXIAPSCN9AKMT2AL3MBTL1 | |
| SCHEMBL7417336 | 0.91 | NPY1R (0.51) | NPY1RXIAPSCN9AL3MBTL1CCKBR | |
| SCHEMBL7418022 | 0.90 | HDAC1 (0.50) | NPY1RXIAPSCN9APYGL | |
| SCHEMBL7421340 | 0.89 | NPY1R (0.49) | NPY1RXIAPSCN9ACCKBRPYGL | |
| SCHEMBL7421160 | 0.89 | SCN9A (0.48) | NPY1RSCN9ACCKBR | |
| SCHEMBL649566 | 0.88 | NPY1R (0.52) | NPY1RXIAPSCN9AKMT2AL3MBTL1 | |
| SCHEMBL5132457 | 0.88 | NPY1R (0.52) | NPY1RXIAPSCN9AKMT2AL3MBTL1 | |
| SCHEMBL649567 | 0.88 | NPY1R (0.52) | NPY1RXIAPSCN9AKMT2AL3MBTL1 | |
| SCHEMBL5651533 | 0.88 | NPY1R (0.52) | NPY1RXIAPSCN9AKMT2AL3MBTL1 | |
| SCHEMBL7421660 | 0.88 | ACE (0.57) | NPY1RSCN9ACCKBRPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |