Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19513862 | 1.00 | TSHR (0.47) | TSHRKMT2APTGS1PTGS2MEN1 | |
| SCHEMBL19513822 | 1.00 | TSHR (0.47) | TSHRKMT2APTGS1PTGS2MEN1 | |
| SCHEMBL9151143 | 1.00 | TSHR (0.47) | TSHRKMT2APTGS1PTGS2MEN1 | |
| SCHEMBL2944990 | 0.98 | TSHR (0.49) | TSHRKMT2APTGS1PTGS2MEN1 | |
| SCHEMBL7103779 | 0.93 | KMT2A (0.47) | TSHRKMT2APTGS1PTGS2MEN1 | |
| SCHEMBL855306 | 0.93 | TSHR (0.50) | TSHRKMT2AMEN1ADRA1BRAB9A | |
| SCHEMBL1627525 | 0.88 | CYP1A2 (0.52) | TSHRKMT2AMEN1RAB9A | |
| SCHEMBL443220 | 0.85 | TSHR (0.53) | TSHRKMT2AMEN1GAARAB9A | |
| SCHEMBL31632694 | 0.85 | PIK3CD (0.52) | TSHRKMT2AMEN1ADRA1B | |
| SCHEMBL19514132 | 0.85 | PIK3CD (0.52) | TSHRKMT2AMEN1ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207710-B1 | FOR THERAPY OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. | 2001-03-27 | — | — | US | disclosed |
| US-4543216-A | REACTING A VINYL BENZYL HALIDE WITH AN AMINO ACID OR AMINO SULFONIC ACID | NIPPON PAINT CO., LTD. (JP) | 1985-09-24 | — | — | US | disclosed |
| US-4452746-A | TO MODIFY PROPERTIES OF HIGH MOLECULAR WEIGHT COMPOUNDS | NIPPON PAINT CO., LTD. (JP) | 1984-06-05 | — | — | US | disclosed |