Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417540 | 0.95 | TACR1 (0.89) | TACR1 | |
| SCHEMBL7416640 | 0.94 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7418622 | 0.94 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7417465 | 0.91 | TACR1 (0.90) | TACR1 | |
| SCHEMBL7423780 | 0.90 | TACR1 (0.80) | TACR1 | |
| SCHEMBL8915244 | 0.88 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7419035 | 0.87 | TACR1 (0.87) | TACR1 | |
| SCHEMBL7425121 | 0.86 | TACR1 (0.73) | TACR1 | |
| SCHEMBL7386152 | 0.85 | TACR1 (0.93) | TACR1 | |
| SCHEMBL3514822 | 0.85 | TACR1 (0.93) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013646-A1 | N,N-DIACYLPIPERAZINE TACHYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | claimed |
| US-5344830-A | Anitinflammatory, cardiovascular, analgesic, central nervous system | MERCK & CO., INC. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994013646-A1 | N,N-DIACYLPIPERAZINE TACHYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |