Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.77 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392018 | 0.98 | NPC1 (0.74) | NPC1RAB9AHTR7PTPN1L3MBTL1 | |
| SCHEMBL7005013 | 0.98 | NPC1 (0.74) | NPC1RAB9AHTR7PTPN1L3MBTL1 | |
| SCHEMBL11282894 | 0.96 | NPC1 (0.77) | NPC1RAB9AHTR7PTPN1L3MBTL1 | |
| SCHEMBL9680520 | 0.92 | NPC1 (0.91) | NPC1RAB9AHTR7PTPN1L3MBTL1 | |
| SCHEMBL9680984 | 0.90 | NPC1 (0.87) | NPC1RAB9AHTR7PTPN1L3MBTL1 | |
| SCHEMBL1040636 | 0.90 | NPC1 (0.87) | NPC1RAB9AHTR7PTPN1L3MBTL1 | |
| SCHEMBL9990825 | 0.90 | PTPN1 (0.72) | NPC1RAB9AHTR7PTPN1HTT | |
| SCHEMBL3424496 | 0.90 | NPC1 (0.87) | NPC1RAB9AHTR7PTPN1L3MBTL1 | |
| SCHEMBL7365742 | 0.88 | NPC1 (0.61) | NPC1RAB9AHTR7PTPN1L3MBTL1 | |
| SCHEMBL7370268 | 0.88 | NPC1 (0.61) | NPC1RAB9AHTR7PTPN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250537-A | Treating psychoses | SCIOS NOVA INC. (US) | 1993-10-05 | — | — | US | disclosed |