Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.41 |
| ▸ | F7 | P08709 | 14/20 | 0.41 |
| ▸ | F3 | P13726 | 13/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.41 |
| ▸ | F2 | P00734 | 11/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883570 | 0.90 | F7 (0.52) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5883607 | 0.83 | CYP2C9 (0.35) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5882844 | 0.82 | F7 (0.45) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5883206 | 0.80 | F10 (0.38) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5883155 | 0.80 | F7 (0.41) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5883527 | 0.80 | F7 (0.52) | F10F7F3PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL5883090 | 0.79 | F7 (0.51) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5882190 | 0.79 | F10 (0.50) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5883062 | 0.79 | F7 (0.47) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5882615 | 0.78 | F10 (0.39) | F10F7F3PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |