Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.53 |
| ▸ | F10 | P00742 | 5/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414460 | 0.97 | F2 (0.53) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7416318 | 0.95 | F2 (0.51) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7416495 | 0.94 | F2 (0.51) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7415361 | 0.94 | F2 (0.53) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7415592 | 0.91 | F2 (0.63) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7416669 | 0.91 | F2 (0.48) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7418824 | 0.91 | F2 (0.62) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7414149 | 0.90 | F2 (0.52) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7421015 | 0.89 | F2 (0.51) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7421039 | 0.88 | F2 (0.54) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |