SCHEMBL741917

SCHEMBL741917

CCCCCCCCCCCCCNOCCC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 9/20 0.46
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
PPARA Q07869 2/20 0.41
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
ADH7 P40394 1/20 0.41
THRB P10828 1/20 0.40
CA1 P00915 5/20 0.39
CA2 P00918 5/20 0.39
CA9 Q16790 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11647925 1.00 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL27889703 1.00 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL22444767 1.00 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL10821057 0.97 TSHR (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL466284 0.90 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL10820853 0.90 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL6027841 0.90 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL10520996 0.90 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL16143788 0.90 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B
SCHEMBL28554627 0.90 EPHX1 (0.46) EPHX1TSHRALDH1A1PPARAADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2707470-B1 AROMATIC IMIDES AS LUBRICANT ADDITIVES LUBRIZOL CORP (US) 2021-04-21 EP disclosed
EP-2430134-B1 METHOD USING IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS LUBRIZOL CORP (US) 2016-03-16 EP disclosed
US-9006156-B2 Imides and bis-imides as friction modifiers in lubricants THE LUBRIZOL CORPORATION (US) 2015-04-14 US disclosed
US-8455410-B2 Lubricating oil composition INFINEUM INTERNATIONAL LIMITED (GB) 2013-06-04 US disclosed
US-20120122744-A1 Imides and Bis-Imides as Friction Modifiers in Lubricants THE LUBRIZOL CORPORATION (US) 2012-05-17 US disclosed
EP-2453000-A1 Lubricating Oil Composition comprising a hydrogenated imide derived from a Diels-Alder adduct of maleic anhydride and a furan Infineum International Limited (GB) 2012-05-16 EP disclosed
US-20120111299-A1 LUBRICATING OIL COMPOSITION INFINEUM INTERNATIONAL LIMITED (GB) 2012-05-10 US disclosed
EP-2430134-A1 IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS The Lubrizol Corporation (US) 2012-03-21 EP disclosed
WO-2010132318-A1 IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-11-18 WO disclosed