SCHEMBL7419633

SCHEMBL7419633

COc1ccc2c(c1OC)C(=O)N(CSc1nnnn1-c1ccccc1)S2(=O)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 19/20 1.00
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9690823 0.91 ELANE (0.83) ELANE
SCHEMBL7416544 0.85 ELANE (1.00) ELANE
SCHEMBL7312226 0.85 ELANE (1.00) ELANEGAA
SCHEMBL7311074 0.84 ELANE (1.00) ELANEGAA
SCHEMBL7420488 0.82 ELANE (1.00) ELANE
SCHEMBL8477711 0.82 ELANE (0.86) ELANE
SCHEMBL7414358 0.82 ELANE (1.00) ELANE
SCHEMBL7414675 0.81 ELANE (1.00) ELANE
SCHEMBL7418324 0.81 ELANE (1.00) ELANE
SCHEMBL7314163 0.80 ELANE (0.78) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471756-B1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF SANOFI SA (FR) 1997-10-29 EP claimed
WO-1990013549-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF STERLING WINTHROP INC. (US) 1990-11-15 WO claimed