Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314163 | 0.88 | ELANE (0.78) | ELANEALDH1A1PKM | |
| SCHEMBL7420488 | 0.88 | ELANE (1.00) | ELANE | |
| SCHEMBL7418531 | 0.87 | ELANE (1.00) | ELANEALDH1A1PKM | |
| SCHEMBL7414675 | 0.87 | ELANE (1.00) | ELANE | |
| SCHEMBL7416331 | 0.85 | ELANE (1.00) | ELANE | |
| SCHEMBL7420790 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL7310549 | 0.84 | ELANE (1.00) | ELANEALDH1A1PKM | |
| SCHEMBL7420501 | 0.83 | ELANE (1.00) | ELANE | |
| SCHEMBL7414358 | 0.83 | ELANE (1.00) | ELANEALDH1A1 | |
| SCHEMBL7420954 | 0.82 | ELANE (1.00) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471756-B1 | SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF | SANOFI SA (FR) | 1997-10-29 | — | — | EP | claimed |
| EP-0471756-A4 | SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF | — | 1992-04-08 | — | — | EP | claimed |
| EP-0471756-A1 | SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF. | STERLING WINTHROP INC (US) | 1992-02-26 | — | — | EP | claimed |
| WO-1990013549-A1 | SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1990-11-15 | — | — | WO | claimed |